NeoGen EVO is nitrogen plasma skin regeneration — a clinical, practitioner-led treatment that works beneath the surface to renew skin from within. Explore exactly how it works, who it suits, and how to prepare and recover.
Plasma is genuinely versatile — it is cleared for several medical indications and supports a wide range of skin-quality concerns. Here is everything it addresses, with the science behind each.
How plasma remodels the dermis to soften atrophic acne scars
Plasma delivers controlled thermal energy into the dermis, stimulating a wave of new collagen that gradually fills and softens depressed scars from below.
Acne scars form when inflammation damages the dermal collagen scaffold, leaving the surface tethered and depressed. Plasma heats the dermis without removing the surface, triggering the skin's own remodelling response — fibroblasts lay down fresh collagen along the line of cleavage between the treated zones.
Because the intact epidermis is preserved as a natural dressing, healing is more controlled than with fully ablative resurfacing, which matters on skin already marked by scarring.
How and why plasma addresses sun-induced pre-cancerous lesions
Plasma delivers a controlled thermal pulse that causes the affected patches to flake away from beneath, while the intact outer skin stays in place as a natural protective dressing.
Rather than targeting a single pigment or vessel, plasma deposits energy evenly across the whole surface. The sun-damaged cells are thermally modified and shed during healing.
Crucially, biopsies show the underlying skin itself improves — not just the visible lesion — which is what makes plasma interesting for field sun-damage as well as discrete lesions.
How plasma treats these benign, raised "stuck-on" growths
Plasma delivers thermal energy that sublimates the raised lesion tissue layer by layer, allowing it to dry, darken and shed as the skin beneath renews.
Seborrheic keratoses are benign growths that sit on the skin surface and can look waxy or "stuck on". Plasma treats them without a scalpel or freezing, thermally modifying the lesion so it desiccates and flakes away over the following days.
Because the treatment is non-contact and the surrounding skin is preserved, it can be a refined option for these lesions, including in cosmetically sensitive areas.
How plasma addresses superficial pigmented marks and lesions
Plasma thermally modifies superficial pigmented and benign lesions so they shed during healing, while the intact surface protects the skin beneath.
Superficial pigmented lesions and certain benign marks can be treated by plasma's controlled surface energy. The treated tissue desiccates and flakes away as fresh skin forms.
Plasma is not pigment-selective like some lasers, which is part of why a careful assessment of the lesion type matters before treatment.
How plasma softens rhytides, including the delicate eye area
Plasma heats the dermis to stimulate fresh collagen and elastin, smoothing the skin's surface and softening fine lines and deeper rhytides over time.
Lines deepen as the dermal collagen and elastin scaffold weakens. Plasma's thermal energy prompts a remodelling response — new collagen is laid down, thickening and firming the skin so lines soften from within.
Because the epidermis is preserved, plasma can be used around the eyes and other delicate areas where the skin is thin.
How plasma firms and tightens through collagen renewal
By heating the dermis and driving neocollagenesis, plasma thickens and firms the skin, gradually improving mild laxity and restoring a tauter quality.
Skin loosens as collagen and elastin decline. Plasma's controlled thermal injury stimulates fibroblasts to build new collagen, which firms and tightens the skin over the months that follow.
It is best suited to mild-to-moderate laxity and skin-quality firming rather than significant sagging, which may need different approaches.
How plasma renews sun-damaged, weathered skin
Plasma treats the whole skin surface, shedding sun-damaged cells and rebuilding the dermis — improving tone, texture and the deeper signs of sun damage together.
Years of sun exposure break down collagen (solar elastosis) and leave uneven tone and rough texture. Plasma addresses this as a field treatment, renewing the surface while stimulating dermal repair beneath.
The non-fractionated approach means the whole area is treated evenly, with no untreated islands.
How plasma renews thin, crinkled skin where it shows most
Plasma is particularly suited to thin, crepey skin — it renews the surface and rebuilds collagen while keeping the delicate epidermis intact as a protective layer.
Crepey skin around the eyes and on the neck is thin and finely wrinkled, with depleted collagen. Plasma renews this skin without removing the surface, which is why it can be used safely on these delicate areas.
New collagen thickens the skin, reducing the crinkled, papery quality over the following months.
Where plasma fits in managing mild-to-moderate active acne
Plasma's thermal energy can reduce certain acne-causing activity and improve skin in mild-to-moderate cases, though it is usually a supporting option rather than first-line.
Plasma generates heat that can affect sebaceous activity and the skin environment. Some reports describe improvement in active acne, but it is not a primary acne therapy.
For most people, active acne is best managed medically first, with plasma considered for the skin quality and scarring that acne leaves behind.
Why plasma is not a primary vascular treatment, and where it may help
Plasma does not selectively target blood vessels, so it is not a first-line treatment for redness, rosacea or thread veins; other modalities are usually preferred.
Redness from rosacea and thread veins comes from dilated blood vessels, which are best addressed by vessel-selective treatments rather than plasma's broad thermal energy.
Plasma may improve overall skin quality in some rosacea-prone skin, but expectations should be realistic and it is rarely the primary choice for redness.
Where plasma may help remodel stretch-marked skin
Plasma can stimulate dermal collagen in stretch-marked skin, which may improve texture and appearance, though the evidence here is more limited than for other concerns.
Stretch marks are areas where the dermis has torn and healed with altered collagen. Plasma's remodelling response may improve the texture and quality of these areas over a course.
Results vary, and stretch marks are among the harder concerns to treat with any modality — honesty about expectations is important.
Well-prepared, well-hydrated skin heals more predictably and gives a better result. Here is how to get ready in the weeks and days beforehand.
NeoGen deposits its energy at the surface, and that heat travels through the skin's own moisture. Well-hydrated skin carries it evenly and predictably — which is exactly why the water and moisturiser in the days before make a real difference to your comfort and your result.
NeoGen leaves the surface intact — the treated skin becomes its own natural dressing while fresh skin forms beneath. Your job now is simple: let it work. Recovery depends on the energy used, so find your level below.
2–4 days · minimal peeling
2–5 days · flaking & peeling
7–10 days · fuller peeling
NeoGen is safe and effective for most people, but like any clinical treatment there are situations where it isn't suitable or needs discussing first. Nothing here rules you out automatically — it simply tells us what to talk through at your consultation.
For your safety, treatment isn't possible in these situations.
These don't necessarily prevent treatment, but we need to know about them.
Easily managed with a little planning ahead of treatment.
This is a guide to help you prepare — it isn't a diagnosis, and it isn't exhaustive. Your full medical history is always reviewed at consultation, where suitability is confirmed for you personally.
Every NeoGen journey starts with a proper assessment of your skin and history, so we can tailor the right plan and energy level for you.